With Dr. Ramesh & Dr. Bharath

Where critical care meets critical thinking

CRITKNOW is a podcast dedicated to unpacking recently published critical care research. We go beyond summaries to provide thoughtful insights into clinical interpretation and the methodological nuances that shape study findings.

Our episodes break down complex statistical concepts and research methods in a clear, accessible way—while keeping the focus firmly on what matters most: clinical relevance and how evidence translates to bedside practice.

Designed primarily for advanced critical care trainees and early-career intensivists, CRITKNOW is equally valuable for anyone trying to navigate and make sense of the rapidly evolving critical care literature.

Latest Episode

TIGRIS Trial

In this episode, we discuss the recently published Tigris trial, which evaluated the role of Polymyxin B hemoadsorption in patients with septic shock. We explore the trial’s rationale, trace the evolution of evidence in this area, examine its analytical approach (Bayesian vs. frequentist), and unpack the results. We also discuss the study’s strengths and limitations, and highlight the key takeaways.

Recent Episodes

SOHO trial: HFNC vs. Standard Oxgen Therapy

Episode - 03

Ketamine vs Etomidate: The RSI trial

Episode - 02

Andromeda-Shock-2

Episode - 01